Ore-13

Ultra-Energon or Ore-13 is a potent form of Energon found in the IDW portion of the Generation 1 continuity family.

'Ultra-Energon, known in raw form as Ore-13, is a substance seemingly found only on Earth. Ore-13 can be purified, in the words of Ratchet, into "... baseline Energon, but with a twist." When applied directly to the systems of a Transformer via a modified delivery capsule, it grants that Transformer a phenomenal boost in overall capability."

Ultra-Energon is an artifical substance created by the Decepticon scientist Shockwave. He seeded a number of worlds with a potent "distillation" of Energon hundreds of thousands of years ago, designed to initiate a chain reaction which would produce Ultra-Energon ore in plentiful supplies, giving him the balance of power when Energon shortages became inevitable.

When he abandoned the Decepticons a few thousand years ago to continue the plan by stablising the ore before it destroyed the planets, he first arrived on Earth at the end of the last Ice Age. However, he was ambushed by the Dynobots. With Shockwave left buried, along with the Dynobots, by a failsafe Grimlock had left triggering a volcanic eruption in what is now Nevada, USA, it is likely that the other seeded worlds were destroyed, making Earth the only source of the Ultra-Energon ore. Spotlight: Shockwave

When Shockwave's absence was discovered by Megatron, he assigned Bludgeon to investigate Shockwave's plans, and Soundwave to spy on Bludgeon in turn. While Bludgeon discovered the full extent of Shockwave's plans, he fed little of it back to Megatron - and nor did Soundwave. Spotlight: Soundwave

Eventually, Cybertron was devastated by Thunderwing and left uninhabitable. Stormbringer Some time later, however, Bludgeon and his team - still shadowed by Soundwave - sneaked back to begin work on restoring Thunderwing in preparation for creating their own bio-grafted shells to grant them the power Thunderwing had at his disposal. To do this, they needed power, and proceeded to go to Earth in the early 1980s to mine what they had called "Ultra-Energon". Soundwave initially attempted to deal with them, but - on learning their plans for Thunderwing - was shocked, and fought them despite himself. And lost, left locked in alt mode while Laserbeak and Ravage were deactivated. Spotlight: Soundwave

Eventually, they succeeded in restoring Thunderwing with the Ultra-Energon, who proceeded to devastate Nebulos as a test before turning back to Cybertron. Then, however, the drawback of the powerful substance became clear - the Transformer would run twice as fast, but the Ultra-Energon would not last as long, with Thunderwing stopped at the last moment by Optimus Prime. Following Bludgeon's notes, Prime proceeded to go to Earth. Stormbringer

Ore-13

In the meantime, it had been independently discovered there by a Decepticon infiltration team led by Starscream, who, after exhausting a vein of the ore beneath the original command bunker in Nebraska, built a second command bunker over a richer vein in Oregon. Although not enought to give Starscream any appreciable edge over Megatron, both Decepticons and Autobots believed Ore-13 could drastically tip the balance of their interstellar conflict. Infiltration

After Prime's arrival, he came into direct conflict with the Ore-13-enhanced Megatron, and was nearly deactivated, surviving only by downloading his consciousness into his trailer section. However, realising that Ore-13 was Ultra-Energon, he communicated its' weakness to the other Autobots, who successfully ran Megatron down until Prime could return to his body to deliver a coup de gracé. Retrieved by Skywarp, he proceeded to purge his systems completely of the Ultra-Energon in a CR Chamber.

From Teletraan I: The Transformers Wiki, a Wikia wiki.