Jem

Jem is a television program. Any connection to Synergy or Dr. Emmett Benton would be speculative at best.
Fiction
The Transformers cartoon
In Transformers Animated: The AllSpark Almanac II, Vector Prime states that the events of Jem and the Holograms are canon for Primax 984.17 Alpha.
Super-God Masterforce cartoon
A poster advertised Jem in the lobby at CNM TV where Sam met with Hydra and Buster. Lightfoot: A Dramatic Encounter
Notes

- Character models for main characters from Jem were recycled to make crowd fillers in the Transformers episode "B.O.T.".
- The same scripts that were used for the Transformers public service announcements were recycled for several Jem PSAs (the scripts were originally used for G.I. Joe PSAs, in fact).
- Jem and The Transformers share the character of Hector Ramirez.
- Prime Megatron starred in a commercial that featured clips of various shows airing on The Hub, including the original Jem cartoon.