Antimatter

Anti-matter is a powerful energy source though somewhat unstable.

Fiction

Generation 1 cartoon continuity

An anti-matter formula was created by Dr. Alcazar which came to the attention of Megatron who wanted it as a source of energy. He deleted the formula but sent it to Chip Chase. Ultimately, it was learnt that anti-matter was simply too unstable to use. Roll For It

From Teletraan I: The Transformers Wiki, a Wikia wiki.