CNA

CNA is the fundamental genetic material of the Transformer species.

CNA is the genetic material that determines what Transformers are like. Tinkering with it can be dangerous and can have long lasting, negative effects.

Fiction

Transformer genetic material. Watson and Crick eat your heart out.

Generation 2

The existance of Transformer genetic material is first mentioned and seen when Perceptor and others are analyzing The Swarm. They not that its genetic material and cellular structure are identical to that of the Transformers species.

IDW

Out of a malevolent curiousity Jhiaxus alters the CNA (the first time the term is used) of Arcee at her creation to introduce the female gender to the species.

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From Teletraan I: The Transformers Wiki, a Wikia wiki.