Achilles virus

The Achilles virus is a virus created by Shockwave that robs an affected Transformer of the ability to perceive Megatron's weaknesses.

Fiction

IDW Generation 1 comics

Not trusting Overlord, Megatron had him infected with the Achilles virus. When Overlord desired to move against Megatron for daring to constrain him into being just a Phase Sixer, he realized that, despite his skills in strategy and tactics, he was incapable of recognizing Megatron's weakness and exploiting them. As such, he invaded Garrus-9 and, after maintaining control of the prison, released Shockwave so that he could cure Overlord of the Achilles virus. The logical Decepticon agreed to do so in exchange for leaving the planet. Last Stand of the Wreckers #3