Cyber-virus

Megatron's cyber-virus fuses human DNA with Transformer central circuitry. The resulting virus spreads organically, then solidifies into metal, transforming Earth's landscape into a semblance of the planet Cybertron.

Once it begins spreading, the virus is self-sustaining.

Fiction

Dreamwave Generation One continuity

Megatron created the cyber-virus by merging the essences of Lazarus's captured soldiers with the captured Autobots. The process left the Autobots near death, and the humans... not-so-near. Prime Directive #3

Wheeljack invented an anti-viral weapon, directly channeling the Autobots' life-energy to halt the virus's progress and reverse the changes it had wrought. Prime Directive #5 Prime Directive #6

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Notes

• The cyber-virus is not named in the course of "Prime Directive" proper; the term comes from advertising copy hyping upcoming issues.