Prion (Titan)
- Prion is a Titan from the IDW portion of the Generation 1 continuity family.

Prion was one of the Titans created by the legendary Knights of Cybertron to act as a living ship. Partnered with Micronus Prime, Prion made planetfall on a barren world, overseeing the development of a new Transformer civilization until the disastrous arrival of the Black Block Consortia.
Fiction
IDW Generation 1 continuity
Millions of years ago, according to Camien historical records, Prion and the other 12 colony Titans departed Cybertron to found new outposts of Cybertronian civilization. First Contact Prion settled on a planet far away from Cybertron, and the new Transformers birthed from Prion's hot spot developed into a civilization of "Mini-Cons". The peaceful colony met its end when the robo-phobic Black Block Consortia sterilized the planet, killing Prion and leaving no survivors but Nickel, who was found by the Decepticon Justice Division days after the attack. Nickel was known to swear by "Prion's shadow". The Permanent Revolution
Following his revival, Sentinel Prime brought his captive audience of Optimus Prime, Soundwave, and Sovereign to the wreckage of Prion, where Sentinel used it as a backdrop as he monologued about his plans for Optimus. White Heat
After producing a biopic about the life of Starscream, an offended Starscream arranged for Thundercracker to be tricked into visiting Prion so that he could be surreptitiously assassinated. Thundercracker managed to escape his killers and flee to Earth. Starscream: The Movie
Notes
- Prion's planet has thus far gone unnamed, but it is not dissimilar in concept to Micro.
- A prion is a protein-based infectious agent, the most well-known infection perhaps being mad cow disease.

