Nuclear weapon

Nuclear weapons, also known as atom bombs or nukes, are extremely powerful weapons that harness atomic energy.
Fiction
Marvel The Transformers comics
As G.B. Blackrock was preparing to unveil his new his new weapon to deal with the giant robots in the area at the Blackrock Motor Speedway, a journalist asked him if it was true that the weapon fired nuclear missiles. DIS-Integrated Circuits!
During his time in control of the Ark, Shockwave reprogrammed the combat drone Guardian and booby-trapped it with a thermo-nuclear bomb. The Wrath of Guardian! With the bomb's countdown timer ticking, Swoop carried Guardian away from the Ark, saving the Autobot base from the explosion but seemingly at the cost of his own life. The Wrath of Grimlock!
Rhythms of Darkness!
With the North American continent under the control of Galvatron, the governments of the Earth's remaining free nations planned to eliminate the Decepticon threat with a nuclear strike. However, thanks to the efforts of Spike, Lisa, and a handful of Autobots, the US flag was raised above the Decepticon Powerbase as a sign that America was still fighting and the strike was called off. Rhythms of Darkness!
Dreamwave Generation One continuity

As the Autobots and Decepticons fought in San Francisco, General Hallo decided to fire a nuclear missile at the city to wipe out all the Transformers, forcing Superion to sacrifice his life to save everyone else. While the actual missile strike was stopped, the shock wave from the blast still hit the city. Prime Directive #6 San Francisco was contaminated with radiation from the fallout. Hardwired
2005 IDW continuity
Thundercracker's movie Last Laugh: The Life and Death of Chuckles depicted the title character saving the entire world from Cobra Commander's fiendish plot to launch nuclear missiles. Starscream: The Movie
The Cobra terrorist Cesspool, assisted by his mutant Army Ants, held Mexico City to ransom with a nuclear bomb. As G.I. Joe arrived to shut his plot down, Cesspool threatened to detonate his bomb but was taken out by Lady Jaye with a laser javelin to the back. Scarlett's Strike Force #1
Bumblebee Movie Prequel
2019 IDW continuity
The Thraal carried out a policy of deliberate, targeted sterilization of the A'ovan homeworld by bombarding the planet with nuclear weapons. Nautica: Home Though a small population of A'ovan refugees were able to find sanctuary on Cybertron, their planet was left an irradiated wasteland. The World In Your Eyes Part Two

