When a shopping mall is struck by lightning from an energon cloud, the various ordinary objects within it are given life and become the race of tiny transforming robots known as BotBot. By day, they hide in plain sight, but by night, they emerge from hiding and get into all sorts of adventures. These tiny bots have organized themselves into squads based on their stores of origin, but some were left in the lost-and-found when the surge occurred and are treated as outcasts by the others. When these Lost Bots accidentally run afoul of the mall security guard, they must put aside their differences and band together to protect all of the BotBots from being exposed.
BotBots is the first Transformers cartoon to feature a Canadian voice cast since 2006's Cybertron cartoon, though based in Toronto rather than Vancouver.